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Invitrogen™ HOPX Polyclonal Antibody
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Catalog No. PIPA578604
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100 μL
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PIPA578604 100 μL
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Catalog No. PIPA578604 Supplier Invitrogen™ Supplier No. PA578604
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Description

Rabbit Polyclonal Antibody

Positive Control: Human brain Predicted Reactivity: Mouse (91%), Rat (91%), Pig (91%), Bovine (94%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

HOPX is an atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. HOPX acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. HOPX prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. HOPX overexpression causes cardiac hypertrophy and may act as a tumor suppressor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HOPX
Applications Western Blot
Classification Polyclonal
Concentration 0.26 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Hopx
Gene Accession No. Q9BPY8
Gene Alias 1110018K11Rik; 1200015P04Rik; 2300002F06Rik; AI848177; AW490897; Cameo; GIIg15b; global ischemia induced protein GIIG15B; global ischemia-induced gene 15B protein; global ischemia-induced protein 15B; Hdop; HOD; homeobox only domain; homeobox-only protein; homeodomain only protein; homeodomain-only protein; Hop; HOP homeobox; Hopx; LAGY; Lung cancer-associated Y protein; mOB1; NECC1; not expressed in choriocarcinoma clone 1; Not expressed in choriocarcinoma protein 1; OB1; Obl; odd homeobox 1; odd homeobox protein 1; SMAP31; Toto
Gene Symbols Hopx
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human HOPX. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84525
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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