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Invitrogen™ HOPX Polyclonal Antibody
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Catalog No. PIPA5114744
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100 μL
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PIPA5114744 100 μL
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Catalog No. PIPA5114744 Supplier Invitrogen™ Supplier No. PA5114744
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total HOP.

HOPX is an atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. HOPX acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. HOPX prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. HOPX overexpression causes cardiac hypertrophy and may act as a tumor suppressor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HOPX
Applications Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene Hopx
Gene Accession No. Q8R1H0, Q9BPY8
Gene Alias 1110018K11Rik; 1200015P04Rik; 2300002F06Rik; AI848177; AW490897; Cameo; GIIg15b; global ischemia induced protein GIIG15B; global ischemia-induced gene 15B protein; global ischemia-induced protein 15B; Hdop; HOD; homeobox only domain; homeobox-only protein; homeodomain only protein; homeodomain-only protein; Hop; HOP homeobox; Hopx; LAGY; Lung cancer-associated Y protein; mOB1; NECC1; not expressed in choriocarcinoma clone 1; Not expressed in choriocarcinoma protein 1; OB1; Obl; odd homeobox 1; odd homeobox protein 1; SMAP31; Toto
Gene Symbols Hopx
Host Species Rabbit
Immunogen A synthesized peptide derived from human HOPX(Accession Q9BPY8), corresponding to amino acid residues A40-D73.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 74318, 84525
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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