HOPX Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 114191AP150UL

Catalog No. 50-172-7143

Description

HOPX is an atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. HOPX acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. HOPX prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. HOPX overexpression causes cardiac hypertrophy and may act as a tumor suppressor.

Specifications

• Antigen: HOPX
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HOPX
• Gene Alias: CAMEO, HOD, Homeodomain only protein, HOP, HOP homeobox, HOPX, LAGY, NECC1, OB1, Odd homeobox protein 1, SMAP31, TOTO
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 171160, 74318, 84525
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.26 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q78ZR5, Q8R1H0, Q9BPY8
• Gene Symbols: Hopx
• Immunogen: HOPX Fusion Protein Ag1979
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG