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Invitrogen™ HORMAD2 Polyclonal Antibody
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Catalog No. PIPA543944
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100 μL
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PIPA543944 100 μL
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Catalog No. PIPA543944 Supplier Invitrogen™ Supplier No. PA543944
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Description

Rabbit Polyclonal Antibody

Peptide sequence: VKKLFATSIS CITYLRGLFP ESSYGERHLD DLSLKILRED KKCPGSLHII Sequence homology: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 79%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 82%.

Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen HORMAD2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene HORMAD2
Gene Accession No. Q8N7B1
Gene Alias 4930529M09Rik; CT46.2; HORMA domain containing 2; HORMA domain-containing protein 2; Hormad2
Gene Symbols HORMAD2
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human HORMAD2 (aa 35-84).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 150280
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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