Invitrogen™ HOXA5 Monoclonal Antibody (3E8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA519102

Catalog No. PIMA519102

Description

Peptide Sequence: PAQPQIYPWM RKLHISHDNI GGPEGKRART AYTRYQTLEL EKEFHFNRYL TRRRRIEIAH ALCLSERQIK IWFQNRRMKW KKDNKLKSMS MAAAGGAFRP.

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA5 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.

Specifications

• Antigen: HOXA5
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P20719
• Gene Symbols: HOXA5
• Immunogen: HOXA5 (NP_061975.1, 171 a.a. ~ 270 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 3E8
• Conjugate: Unconjugated
• Gene: HOXA5
• Gene Alias: homeo box 1C; homeo box A5; homeobox A5; homeobox protein Hox-1.3; Homeobox protein Hox-1C; homeobox protein HOXA5; homeobox protein Hox-A5; homeobox protein M2; HOX1; HOX1.3; Hox-1.3; HOX1C; Hox-1C; Hoxa5; Hoxa-5; Unknown (protein for MGC:138007)
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3202
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid