Invitrogen™ HOXA5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA535897

Catalog No. PIPA535897

Description

Recommended positive controls: human HOXA5-transfected 293T. Predicted reactivity: Mouse (96%), Pig (96%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA5 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.

Specifications

• Antigen: HOXA5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HOXA5
• Gene Alias: homeo box 1C; homeo box A5; homeobox A5; homeobox protein Hox-1.3; Homeobox protein Hox-1C; homeobox protein HOXA5; homeobox protein Hox-A5; homeobox protein M2; HOX1; HOX1.3; Hox-1.3; HOX1C; Hox-1C; Hoxa5; Hoxa-5; Unknown (protein for MGC:138007)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3202
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P20719
• Gene Symbols: HOXA5
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 203 of HOXA5.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov