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HOXB4 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985556
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50-198-5556 100 μL
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Catalog No. 50-198-5556 Supplier Bioss Supplier No. BS3650R
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Description

Rabbit Polyclonal Antibody

HOX homeobox genes play a role both in the early stem cell function as well as in later stages of hematopoietic differentiation. HOXB4, specifically, is a homeotic selector gene implicated in self-renewal of definitive HSCs. Expression of HOXB4 in primitive progenitors combined with culture on hematopoietic stroma induced a switch to the definitive HSC phenotype. Activation of WNT signaling in HSCs induced increased expression of HOXB4. Perturbations of HOX gene expression can cause leukemia.

Specifications

Antigen HOXB4
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene HOXB4
Gene Accession No. P17483
Gene Alias BOS_18995; homeo box 2F; homeo box B4; homeo box B4a; homeobox B4; homeobox B4a; homeobox gene B-4; Homeobox protein Hox-2.6; Homeobox protein Hox-2F; Homeobox protein Hox-B4; Homeobox protein Hox-B4a; Homeobox protein Zf-13; HOX2; Hox-2.6; HOX2F; HOXB4; hox-b4; Hoxb-4; Hoxb4 protein; hoxb4a; Hoxb4a variant 2; RGD1560113; sb:eu512; Z-17; zf13; ZF-13
Gene Symbols HOXB4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human HOXB4.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3214
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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