Invitrogen™ HOXB5 Monoclonal Antibody (3F10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA519112

Catalog No. PIMA519112

Description

Peptide Sequence: EGQTPQIFPW MRKLHISHDM TGPDGKRART AYTRYQTLEL EKEFHFNRYL TRRRRIEIAH ALCLSERQIK IWFQNRRMKW KKDNKLKSMS LATAGSAF.

The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxB5 (homeobox protein Hox-B5), also known as HOX2, HU-1, HOX2A, Hox2.1 or HHO.C10, is a member of the Antp homeobox (Hox) family. It is a 269 amino acid long nuclear protein expressed in the central nervous system. HoxB5 contains one homeobox DNAbinding domain and plays a role in the regulation of lung and gut development, providing cells with positional identities on the anterior-posterior body axis.

Specifications

• Antigen: HOXB5
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P09067
• Gene Symbols: HOXB5
• Immunogen: HOXB5 (NP_002138.1, 170 a.a. ~ 267 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Western Blot
• Clone: 3F10
• Conjugate: Unconjugated
• Gene: HOXB5
• Gene Alias: AI385717; HHO.C10; homeo box 2A; homeo box B5; homeobox B5; homeobox protein H24.1; Homeobox protein HHO.C10; homeobox protein Hox-2.1; Homeobox protein Hox-2A; homeobox protein Hox-B5; Homeobox protein Hu-1; homeobox protein Mu-1; HOX2; Hox2.1; Hox-2.1; HOX2A; HOXB5; Hoxb-5; HU-1; RGD1562292
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3215
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid