Invitrogen™ HOXB8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA541172

Catalog No. PIPA541172

Description

Peptide sequence: FQNRRMKWKK ENNKDKFPSS KCEQEELEKQ KLERAPEAAD EGDAQKGDKK Sequence homology: Dog: 100%; Human: 100%; Mouse: 79%; Pig: 100%; Rat: 79%.

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.

Specifications

• Antigen: HOXB8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HOXB8
• Gene Alias: homeo box 2D; homeo box B8; homeobox B8; homeobox gene B8; homeobox protein Hox-2.4; Homeobox protein Hox-2D; homeobox protein Hox-B8; homeobox protein R1a; HOX2; Hox-2.4; Hox2.4 homeobox homolog; HOX2D; Hox2r1a; Hoxb8; Hoxb-8
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3218
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P17481
• Gene Symbols: HOXB8
• Immunogen: Synthetic peptide directed towards the middle region of human HOXB8.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov