Invitrogen™ HOXC12 Monoclonal Antibody (3E1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA519125

Catalog No. PIMA519125

Description

Peptide Sequence: MGEHNLLNPG FVGPLVNIHT GDTFYFPNFR ASGAQLPGLP SLSYPRRDNV CSLSWPSAEP CNGYPQPYLG SPVSLNPPFG RTCELARVED GKGYYREPCA.

The Homeobox (Hox) proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. In mammals, there are four gene clusters encoding Hox proteins, namely HoxA, HoxB, HoxC and HoxD, that are located on different chromosomes, each consisting of 9-11 tandemly arranged genes. HoxC12 (Homeobox C12), also known as Hox3, Hox3F or HOC3F, is a member of the Abd-B homeobox (Hox) family and is encoded by a gene from the HoxC cluster. HoxC12 is a 282 amino acid long nuclear protein that contains one homeobox DNA-binding domain.

Specifications

• Antigen: HOXC12
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P31275
• Gene Symbols: HOXC12
• Immunogen: HOXC12 (NP_776272, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 3E1
• Conjugate: Unconjugated
• Gene: HOXC12
• Gene Alias: HOC3F; homeo box C12; homeobox C12; homeobox protein Hox-3.8; Homeobox protein Hox-3F; Homeobox protein Hox-C12; Homeobox protein Hox-C12 (Hox-3F); HOX3; Hox-3.8; HOX3F; HOXC12; Hoxc-12
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3228
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid