Invitrogen™ HOXD12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599289

Catalog No. PIPA599289

Description

Antibody detects endogenous levels of total HOXD12.

The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxD12 (homeobox D12), also known as HOX4H, is a 275 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. One of several members of the homeobox superfamily, HoxD12 functions as a sequencespecific transcription factor that is important for the correct positioning of developing limb buds on the anterior-posterior axis.

Specifications

• Antigen: HOXD12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HOXD12
• Gene Alias: homeo box D12; homeobox D12; homeobox protein Hox-4.7; Homeobox protein Hox-4H; homeobox protein Hox-5.6; Homeobox protein Hox-D12; Hox 4H; Hox-4.7; Hox-4.7, mouse, homolog of; HOX4H; Hox-5.6; Hoxd12; Hoxd-12
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15432, 3238
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P23812, P35452
• Gene Symbols: HOXD12
• Immunogen: A synthesized peptide derived from human HOXD12(Accession P35452), corresponding to amino acid residues A68-S118.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG