Invitrogen™ HOXD3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590343

Catalog No. PIPA590343

Description

Immunogen sequence: ASQSPERSPP LGGAAGHVAY SGQLPPVPGL AYDAPSPPAF AKSQPNMYGL AAYTAPLSSC LPQQKRYAAP EFEPHPMASN GGGFASANLQ GSPVYVGGNF VESMAPASGP VFNLGHLSHP SSASVDYSCA AQIPGNHHHG PCDPHPTYTD LSAHHSSQGR LPEAPKLTHL; Positive Samples: Mouse liver, Mouse spinal cord, Rat spinal cord, Rat liver; Cellular Location: Nucleus.

HOXD3 (homeobox D3) belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that remove the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. HOXD3 may play a role in the regulation of cell adhesion processes.

Specifications

• Antigen: HOXD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Hoxd3
• Gene Alias: homeo box D3; homeo box D4; homeobox D3; Homeobox gene D3; homeobox protein Hox-4.1; Homeobox protein Hox-4A; homeobox protein Hox-D3; Homeobox protein MH-19; homeobox protein R6; HOX1D; HOX4; Hox-4.1; Hox-4.1, mouse, homolog of; HOX4A; Hox4r6; Hox-5.5; HOXD3; Hoxd-3; MGC10470
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15434, 3232
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.13 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P09027, P31249
• Gene Symbols: Hoxd3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 263-432 of human HOXD3 (NP_0088293).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov