Invitrogen™ HP1 beta Monoclonal Antibody (4E12)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA521203

Catalog No. PIMA521203

Description

Peptide Sequence: GKKQNKKKVE EVLEEEEEEY VVEKVLDRRV VKGKVEYLLK WKGFSDEDNT WEPEENLDCP DLIAEFLQSQ KTAHETDKSE GGKRKADSDS EDKGEESK.

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specifications

• Antigen: HP1 beta
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P83916
• Gene Symbols: CBX1
• Immunogen: CBX1 (NP_006798.1, 2 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 4E12
• Conjugate: Unconjugated
• Gene: CBX1
• Gene Alias: CBX; Cbx1; Cbx-rs2; chromobox 1; chromobox homolog 1; chromobox homolog 1 (HP1 beta homolog Drosophila ); chromobox protein homolog 1; E430007M08Rik; heterochromatin protein 1 homolog beta; heterochromatin protein 1-beta; heterochromatin protein p25; heterochromatin protein p25 beta; HGNC:1551; HP1 beta; HP1 beta homolog; HP1B; Hp1beta; HP1-BETA; HP1Hsbeta; HP1Hs-beta; M31; MOD1; modifier 1 protein; p25beta
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10951, 360609
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid