Invitrogen™ HP1 beta Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518433

Catalog No. PIPA518433

Description

This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specifications

• Antigen: HP1 beta
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CBX1
• Gene Alias: CBX; Cbx1; Cbx-rs2; chromobox 1; chromobox homolog 1; chromobox homolog 1 (HP1 beta homolog Drosophila ); chromobox protein homolog 1; E430007M08Rik; heterochromatin protein 1 homolog beta; heterochromatin protein 1-beta; heterochromatin protein p25; heterochromatin protein p25 beta; HGNC:1551; HP1 beta; HP1 beta homolog; HP1B; Hp1beta; HP1-BETA; HP1Hsbeta; HP1Hs-beta; M31; MOD1; modifier 1 protein; p25beta
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 10951
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P83916
• Gene Symbols: CBX1
• Immunogen: Synthetic peptide sequence (QSQKTAHETDKSE) corresponding to the internal amino acids of CBX1 (aa 69-82).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG