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Invitrogen™ HP1 gamma Polyclonal Antibody
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Catalog No. PIPA5120805
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100 μL
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PIPA5120805 100 μL
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Catalog No. PIPA5120805 Supplier Invitrogen™ Supplier No. PA5120805
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Description

Rabbit Polyclonal Antibody

Positive test controls include: HeLa, MCF-7, 293T, A-549, NCI-H460, Mouse brain, Mouse lung, Mouse spleen. The target is usually found in the following locations: Nucleus. Immunogen sequence: MASNKTTLQK MGKKQNGKSK KVEEAEPEEF VVEKVLDRRV VNGKVEYFLK WKGFTDADNT WEPEENLDCP ELIEAFLNSQ KAGKEKDGTK RKSLSDSESD DSKSKKKRDA ADKPRGFARG LDPERIIGAT DSSGELMFLM KWKDSDEADL VLAKEANMKC PQIVIAFYEE RLTWHSCPED EAQ.

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HP1 gamma
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.26 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Cbx3
Gene Accession No. P23198, Q13185
Gene Alias CBX3; chromobox 3; chromobox homolog 3; chromobox homolog 3 (HP1 gamma homolog, Drosophila); chromobox protein homolog 3; chromobox-like protein 3; HECH; heterochromatin protein 1 gamma; heterochromatin protein 1 homolog gamma; heterochromatin protein HP1 gamma; heterochromatin-like protein 1; HGNC:1553; HP1 gamma; HP1 gamma homolog; HP1g; HP1-GAMMA; HP1Hs-gamma; HPy; M32; Modifier 2 protein; OTTHUMP00000202463
Gene Symbols Cbx3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-183 of human HP1 gamma/HP1 gamma/CBX3 (NP_0092072).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11335, 12417, 297093
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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