Invitrogen™ HPa2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121181

Catalog No. PIPA5121181

Description

Positive test controls include: BT-474, 22Rv1, HeLa, SKOV3, Mouse brain, Mouse small intestine, Mouse testis, Mouse uterus, Rat brain. The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space. Immunogen sequence: GDRRPLPVDR AAGLKEKTLI LLDVSTKNPV RTVNENFLSL QLDPSIIHDG WLDFLSSKRL VTLARGLSPA FLRFGGKRTD FLQFQNLRNP AKSRGGPGPD YYLKNYEDDI VRSDVALDKQ KGCKIAQHPD VMLELQREKA AQMHLVLLKE QFSNTYSNLI LTARSLDKLY NFADCSGLHL IFALNALRRN PNNSWNSSSA L.

This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants.

Specifications

• Antigen: HPa2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HPSE2
• Gene Alias: Gm968; heparanase 2; heparanase 2 (inactive); heparanase 3; heparanase-2; heparanase-like protein; Hpa2; HPR2; Hpse2; Inactive heparanase-2; UFS; UFS1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 368128, 545291, 60495
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.67 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: B2RY83, Q8WWQ2
• Gene Symbols: HPSE2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 42-242 of human HPSE2 (NP_068600.4).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG