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Invitrogen™ HPD Monoclonal Antibody (D1), Invitrogen™
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Catalog No. FEMA550967
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200 μL
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FEMA550967 200 μL
FEMA550968 20 μL
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Catalog No. FEMA550967 Supplier Invitrogen™ Supplier No. MA550967
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Description

Mouse Monoclonal Antibody

The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity (1-3). Recently, a serine protease has been isolated, which is released from the mitochondria upon induction of apoptosis by apoptotic stimuli. This protein called Omi/HtrA2 is a mitochondrial protein that binds to IAP (4). Like Smac/DIABLO, the mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N terminus. The deregulated expression of Omi in the cytoplasm of mammalian cells induces apoptosis indicating that Omi could participate in the mitochondrial apoptotic pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HPD
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone D1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
Gene Hpd
Gene Accession No. P32754, Q02110
Gene Alias 4H GLOD3; 4-H HPPDASE; 4HPPD; 4-HPPD; 4-hydroxyphenylpyruvate dioxygenase; 4-hydroxyphenylpyruvic acid dioxygenase; 4-hydroxyphenylpyruvic acid oxidase; f Alloantigen; F liver antigen; f protein; Fla; Flp; GLOD3; glyoxalase domain containing 3; HPD; Hppd; HPPDASE; Laf; PPD
Gene Symbols Hpd
Host Species Mouse
Immunogen Recombinant Human HPD protein, Thr2-Met393 (Accession #P32754).
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3242, 397443
Target Species Human, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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