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HPR Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA548124

Catalog No. PA548124

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011] Primate-specific plasma protein associated with apolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL). This HDL particle, termed trypanosome lytic factor-1 (TLF-1), mediates human innate immune protection against many species of African trypanosomes. Binds hemoglobin with high affinity and may contribute to the clearance of cell-free hemoglobin to allow hepatic recycling of heme iron.
Specifications

Specifications

HPR
Polyclonal
PBS with 0.09% sodium azide
P00739
Haptoglobin-related protein, HPR
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
3250
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
HPR
Liquid
HPR
KLH conjugated synthetic peptide between 212-240 amino acids from the Central region of human HPR.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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