HRAS Rabbit anti-Human, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-0292	150 μL

Catalog No. 50-173-0292 Supplier Proteintech Group Inc Supplier No. 155311AP150UL

Description

Rabbit Polyclonal Antibody

This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.

Specifications

• Antigen: HRAS
• Applications: Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.23 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: HRAS
• Gene Accession No.: P01112, P20171
• Gene Alias: C BAS/HAS, C H RAS, C HA RAS1, CTLO, GTPase HRas, H Ras 1, H RASIDX, Ha Ras, HAMSV, HRAS, HRAS1, K RAS, p21ras, RASH1, Transforming protein p21
• Gene Symbols: HRAS
• Host Species: Rabbit
• Immunogen: HRAS Fusion Protein Ag7704
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 293621, 3265
• Target Species: Human, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG