Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

HRG beta-1 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

$250.00 - $2175.00

Specifications

Antigen HRG beta-1
Concentration 0.1-1.0 mg/mL
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Biotin
View More Specs

Products 3
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
500P288BT25
Encompass_Preferred
View Documents
Invitrogen™
500P288BT25UG
25 μg
Each for $250.00
Only null left
Add to Cart
 
500P288BT50
Encompass_Preferred
View Documents
Invitrogen™
500P288BT50UG
50 μg
Each for $319.00
Only null left
Add to Cart
 
50-271-8537
Encompass_Preferred
View Documents
Invitrogen™
500P288BT500UG
500 μg
Each for $2,175.00
Only null left
Add to Cart
 
Description

Description

AA Sequence of recombinant protein: SHLVKCAEKE KTFCVNGGEC FMVKDLSNPS RYLCKCPNEF TGDRCQNYVM ASFYKHLGIE FMEAE. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human Heregulinbeta-1. Anti-Human Heregulinbeta-1-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect Human Heregulin-beta1 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human Heregulin-beta1 (500-P288) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human Heregulin-beta1. Western Blot: To detect Human Heregulin-beta1 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Human Heregulin-beta1 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P288BT-1MG will be provided as 2 x 500 μg

Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.
Specifications

Specifications

HRG beta-1
ELISA, Western Blot
Biotin
Rabbit
Human
Q02297
3084
E.coli-derived Recombinant Human Heregulinbeta-1.
Antigen affinity chromatography
Nrg1
0.1-1.0 mg/mL
Polyclonal
Lyophilized
RUO
PBS with no preservative
6030402G23Rik; acetylcholine receptor-inducing activity; ARIA; Breast cancer cell differentiation factor p45; D230005F13Rik; GGF; GGF2; GGFII; Glial growth factor; glial growth factor 2; heregulin; heregulin, alpha (45kD, ERBB2 p185-activator); Hgl; HRG; HRG1; HRGA; HRGalpha; MST131; MSTP131; NDF; Neu differentiation factor; neuregulin 1; neuregulin 1 type III beta 3; Neuregulin-1; Nrg1; NRG1-IT2; Pro-neuregulin-1, membrane-bound isoform; pro-NRG1; sensory and motor neuron derived factor; Sensory and motor neuron-derived factor; SMDF; type I neuregulin 1; type III neuregulin 1
Nrg1
Primary
-20°C
Videos
SDS
Documents

Documents

Product Certifications
Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.