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Invitrogen™ HS3ST1 Polyclonal Antibody
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Catalog No. PIPA582007
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100 μL
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PIPA582007 100 μL
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Catalog No. PIPA582007 Supplier Invitrogen™ Supplier No. PA582007
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TQVFYNHMQK HKPYPSIEEF LVRDGRLNVD YKALNRSLYH VHMQNWLRFF PLRHIHIVDG DRLIRDPFPE IQKVERFLKL SPQINASNFY FNKTKGFYCL RDSGRDRCLH ESKGRAHPQV DPKLLNKLHE YFHEPNKKFF ELVGR Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 91%.

HS3ST1 is the rate limiting enzyme for synthesis of HSact. HS3ST1 performs the crucial step modification in the biosynthesis of anticoagulant heparan sulfate (HSact) that is to complete the structure of the antithrombin pentasaccharide binding site. Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It possesses both heparan sulfate glucosaminyl 3-O-sulfotransferase activity, anticoagulant heparan sulfate conversion activity, and is a rate limiting enzyme for synthesis of anticoagulant heparan. This enzyme is an intraluminal Golgi resident protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HS3ST1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene HS3ST1
Gene Accession No. O14792
Gene Alias 3OST; 3-Ost; 3OST1; 3-OST-1; D5Wsu110e; h3-OST-1; heparan sulfate; heparan sulfate (glucosamine) 3-O-sulfotransferase 1; heparan sulfate 3-O-sulfotransferase 1; heparan sulfate 3-O-sulfotransferase-1; heparan sulfate 3-O-sulfotransferase-1 precursor; heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1; Heparan sulfate glucosamine 3-O-sulfotransferase 1; heparan sulfate-glucosamine 3-sulfotransferase 1; heparin-glucosamine 3-O-sulfotransferase; HS3ST1; Hsg3ost
Gene Symbols HS3ST1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human HS3ST1. Recombinant protein control fragment (Product #RP-102159).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9957
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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