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Invitrogen™ HSD11B1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA586683
Description
Purity is > 95% by SDS-PAGE.
HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, HSD11B1 can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.
Specifications
HSD11B1 | |
Polyclonal | |
Unconjugated | |
Hsd11b1 | |
11 beta-hydroxysteroid dehydrogenase type 1; 11beta-HSD type 1; 11-beta-HSD1; 11beta-HSD1; 11beta-HSD-1; 11beta-HSD1A; 11-beta-hydroxysteroid dehydrogenase; 11-beta-hydroxysteroid dehydrogenase 1; 11-beta-hydroxysteroid dehydrogenase type 1; 11beta-hydroxysteroid dehydrogenase type 1; 11-DH; Corticosteroid 11-beta-dehydrogenase isozyme 1; Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A); cortocosteroid 11-beta dehydrogenase; CORTRD2; HDL; HSD11; HSD11B; Hsd11b1; HSD11L; hydroxysteroid (11-beta) dehydrogenase 1; hydroxysteroid 11-beta dehydrogenase 1; hydroxysteroid dehydrogenase, 11 beta type 1; LRRGT00065; MGC13539; OTTHUMP00000034650; SDR26C1; short chain dehydrogenase/reductase family 26C member 1; short chain dehydrogenase/reductase family 26C, member 1; short-chain reductase; short-chain reductase/dehydrogenase | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
15483, 25116, 3290 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
P16232, P28845, P50172 | |
Hsd11b1 | |
Synthetic peptide, corresponding to amino acids 43-88 of Human HSD11B1. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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