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HSD11B1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501726721 Shop All Proteintech Group Inc Products
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50-172-6721 150 μL
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Catalog No. 50-172-6721 Supplier Proteintech Group Inc Supplier No. 109281AP150UL
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Description

Rabbit Polyclonal Antibody

HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, HSD11B1 can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children.The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.

Specifications

Antigen HSD11B1
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.24 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene HSD11B1
Gene Accession No. P16232, P28845, P50172
Gene Alias 11 beta HSD1, 11 DH, HDL, HSD11, HSD11B, HSD11B1, HSD11L, SDR26C1
Gene Symbols HSD11B1
Host Species Rabbit
Immunogen HSD11B1 Fusion Protein Ag1361
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15483, 25116, 3290
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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