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Invitrogen™ HSD17B4 Polyclonal Antibody
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Catalog No. PIPA522367
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100 μL
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PIPA522367 100 μL
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Catalog No. PIPA522367 Supplier Invitrogen™ Supplier No. PA522367
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HeLa, mouse brain. Predicted reactivity: Mouse (92%), Rat (92%), Zebrafish (85%), Xenopus laevis (81%), Pig (87%), Chicken (84%), Bovine (87%), Guinea pig (85%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Peroxisomal multifunctional enzyme type 2 is a protein that in humans is encoded by the HSD17B4 gene. The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HSD17B4
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.66 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene HSD17B4
Gene Accession No. P51659, P51660
Gene Alias (3R)-hydroxyacyl-CoA dehydrogenase; 17[b]-HSD; 17beta-estradiol dehydrogenase type IV; 17-beta-HSD; 17-beta-HSD 4; 17-beta-HSD IV; 17-beta-hydroxysteroid dehydrogenase 4; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; 4; beta-hydroxyacyl dehydrogenase; beta-keto-reductase; D-3-hydroxyacyl-CoA dehydratase; D-bifunctional protein; D-bifunctional protein, peroxisomal; DBP; Edh17b4; Enoyl-CoA hydratase 2; Hsd17b4; hydroxysteroid (17-beta) dehydrogenase 4; hydroxysteroid 17-beta dehydrogenase 4; hydroxysteroid dehydrogenase 4; MFE-2; MFP2; Mfp-2; MPF-2; Multifunctional protein 2; perMFE-2; peroxisomal multifunctional enzyme type 2; peroxisomal multifunctional enzyme type II; peroxisomal multifunctional protein 2; PRLTS1; SDR8C1; Short chain dehydrogenase/reductase family 8C member 1; short chain dehydrogenase/reductase family 8C, member 1
Gene Symbols HSD17B4
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human HSD17B4. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15488, 3295
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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