Invitrogen™ HSD17B6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579406

Catalog No. PIPA579406

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Human Placenta Tissue, MCF-7 whole cell. IHC: human liver cancer tissue.

The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist.

Specifications

• Antigen: HSD17B6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HSD17B6
• Gene Alias: 17-beta-HSD 6; 17-beta-HSD6; 17betaHSD9; 17-beta-HSD9; 17-beta-hydroxysteroid dehydrogenase type 6; 3(alpha->beta)-hydroxysteroid epimerase; 3(alpha->beta)-hydroxysteroid epimerasel; 3-alpha->beta-HSE; 3-alpha->beta-hydroxysteroid epimerase; 3-hydroxysteroid epimerase; Gm182; Hsd17b6; Hsd17b9; HSE; hydroxysteroid (17-beta) dehydrogenase 6; hydroxysteroid (17-beta) dehydrogenase 6 homolog; hydroxysteroid (17-beta) dehydrogenase 9; hydroxysteroid 17-beta dehydrogenase 6; hydroxysteroid 17-beta dehydrogenase 9; hypothetical protein LOC533086; NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase; oxidative 17 beta hydroxysteroid dehydrogenase type 6; oxidative 3-alpha hydroxysteroid dehydrogenase; oxidative 3-alpha-hydroxysteroid-dehydrogenase; oxidoreductase; Rdh8; retinol dehydrogenase; RODH; SDR9C6; Short chain dehydrogenase/reductase family 9C member 6; short chain dehydrogenase/reductase family 9C, member 6
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8630
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
• Gene Accession No.: O14756
• Gene Symbols: HSD17B6
• Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human HSD17B6 (300-317aa SLADYILTRSWPKPAQAV).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG