Invitrogen™ HSD17B6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528926

Catalog No. PIPA528926

Description

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji. Predicted reactivity: Rhesus Monkey (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist.

Specifications

• Antigen: HSD17B6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HSD17B6
• Gene Alias: 17-beta-HSD 6; 17-beta-HSD6; 17betaHSD9; 17-beta-HSD9; 17-beta-hydroxysteroid dehydrogenase type 6; 3(alpha->beta)-hydroxysteroid epimerase; 3(alpha->beta)-hydroxysteroid epimerasel; 3-alpha->beta-HSE; 3-alpha->beta-hydroxysteroid epimerase; 3-hydroxysteroid epimerase; Gm182; Hsd17b6; Hsd17b9; HSE; hydroxysteroid (17-beta) dehydrogenase 6; hydroxysteroid (17-beta) dehydrogenase 6 homolog; hydroxysteroid (17-beta) dehydrogenase 9; hydroxysteroid 17-beta dehydrogenase 6; hydroxysteroid 17-beta dehydrogenase 9; hypothetical protein LOC533086; NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase; oxidative 17 beta hydroxysteroid dehydrogenase type 6; oxidative 3-alpha hydroxysteroid dehydrogenase; oxidative 3-alpha-hydroxysteroid-dehydrogenase; oxidoreductase; Rdh8; retinol dehydrogenase; RODH; SDR9C6; Short chain dehydrogenase/reductase family 9C member 6; short chain dehydrogenase/reductase family 9C, member 6
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8630
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.71 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O14756
• Gene Symbols: HSD17B6
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 317 of Human HSD17B6.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov