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Invitrogen™ HSD3B7 Polyclonal Antibody
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Catalog No. PIPA5101352
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PIPA5101352 100 μL
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Catalog No. PIPA5101352 Supplier Invitrogen™ Supplier No. PA5101352
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total HSD3B7.

This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].
TRUSTED_SUSTAINABILITY

Specifications

Antigen HSD3B7
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene HSD3B7
Gene Accession No. O35048, Q9EQC1, Q9H2F3
Gene Alias 3 beta-hydroxy-delta 5-C27-steroid oxidoreductase; 3 beta-hydroxysteroid dehydrogenase type 7; 3 beta-hydroxysteroid dehydrogenase type VII; 3-beta-HSD VII; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase; AI195443; BB098564; C(27) 3-beta-HSD; C(27)-3BETA-HSD; CBAS1; Cca2; cholest-5-ene-3-be; cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase; Confluent 3Y1 cell-associated 2; HSD3B7; hsd3b7 {ECO:0000312; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; PFIC4; RGD:628727}; SDR11E3; short chain dehydrogenase/reductase family 11E, member 3
Gene Symbols HSD3B7
Host Species Rabbit
Immunogen A synthesized peptide derived from human HSD3B7(Accession Q9H2F3), corresponding to amino acid residues R122-E172.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 101502, 246211, 80270
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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