hSET1B Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc IHC00641T

Catalog No. 50-157-2456

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Bovine, Rabbit, Gorilla, Chimpanzee, Northern white-cheeked gibbon and hirteen-lined ground squir

SETD1B is a component of the SET1 histone methyltransferase (HMT) complex. This complex specifically methylates lysine 4 of histone H3, but only if the neighboring lysine 9 residue is not yet methylated. Methylation of H3K4 represents a specific tag for epigenetic transcriptional activation. SETD1B shows a non-overlapping localization with SETD1A, suggesting that both proteins play a specific role in the epigenetic control of chromatin structure and gene expression.

Specifications

• Antigen: hSET1B
• Classification: Polyclonal
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: Q9UPS6
• Gene Symbols: SETD1B
• Immunogen: Between 350 and 400
• Quantity: 10 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry
• Conjugate: Unconjugated
• Gene: SETD1B
• Gene Alias: SET1B, KMT2G, Histone-lysine N-methyltransferase SETD1B, KIAA1076, Lysine N-methyltransferase 2G, SET domain-containing protein 1B, hSET1B
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23067
• Content And Storage: 4° C
• Form: Liquid