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hSET1B Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501562207
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50-156-2207 100 μL
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Catalog No. 50-156-2207 Supplier Bethyl Laboratories, Inc Supplier No. A302280A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

SETD1B is a component of the SET1 histone methyltransferase (HMT) complex. This complex specifically methylates lysine 4 of histone H3, but only if the neighboring lysine 9 residue is not yet methylated. Methylation of H3K4 represents a specific tag for epigenetic transcriptional activation. SETD1B shows a non-overlapping localization with SETD1A, suggesting that both proteins play a specific role in the epigenetic control of chromatin structure and gene expression.

Specifications

Antigen hSET1B
Applications Immunohistochemistry, Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene SETD1B
Gene Accession No. Q9UPS6
Gene Alias SET1B, KMT2G, Histone-lysine N-methyltransferase SETD1B, KIAA1076, Lysine N-methyltransferase 2G, SET domain-containing protein 1B, hSET1B
Gene Symbols SETD1B
Host Species Rabbit
Immunogen Between 350 and 400
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23067
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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