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Invitrogen™ HSP60 Monoclonal Antibody (4B9/89), Alexa Fluor™ 488
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Catalog No. PIMA3012A48
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PIMA3012A48 50 μL
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Catalog No. PIMA3012A48 Supplier Invitrogen™ Supplier No. MA3012A488
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Description

Mouse Monoclonal Antibody

The MA3012A488 antigen is human placental HSP60. Epitope mapping studies using human HSP60 deletion mutants suggest that this antibody binds either between amino acids 335-366 or 484-547.

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HSP60
Applications Immunocytochemistry
Classification Monoclonal
Clone 4B9/89
Concentration 1 mg/mL
Conjugate Alexa Fluor 488
Formulation PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene HSPD1
Gene Accession No. P10809, P63038, P63039
Gene Alias 60 kDa chaperonin; 60 kDa heat shock protein; 60 kDa heat shock protein, mitochondrial; 60kDa; Chaperonin 60; CPN60; GROEL; heat shock 60kD protein 1 (chaperonin); heat shock 60kDa protein 1; heat shock 60kDa protein 1 (chaperonin); Heat shock protein; heat shock protein 1 (chaperonin); heat shock protein 60; heat shock protein 60 (liver); heat shock protein 65; heat shock protein family D (Hsp60) member 1; heat shock protein, 60 kDa; HLD4; HSP; Hsp60; HSP-60; Hsp60s1; HSP65; HSP-65; Hspd1; Hspd1-30p; HuCHA60; hypothetical protein; I79_011398; mitochondrial matrix protein P1; P1 protein; P60 lymphocyte protein; RCJMB04_7g5; short heat shock protein 60 Hsp60s1; SPG13; Unknown (protein for IMAGE:7943409)
Gene Symbols HSPD1
Host Species Mouse
Immunogen Human placental HSP60.
Purification Method Protein A
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15510, 3329, 63868
Target Species Human, Mouse, Monkey, Rat
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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