Invitrogen™ HSP60 Monoclonal Antibody (A57-E4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA3022

Catalog No. MA3022

Description

MA3-022 detects heat shock protein 60 kDa (HSP60) from bacteria. This antibody detects HSP60 from all three species of Chlamydia, Escherichia coli (GroEL), Salmonella typhimurium, Neisseria gonorrhoeae and Coxiella burnetti. MA3-022 does not cross react with HeLa cell HSP60. MA3-022 has been successfully used in Western blot procedures. By Western blot, this antibody detects a single ~60 kDa protein representing HSP60 from C. trachomatis lysate. The MA3-022 immunogen is recombinant Chlamydia trachomatis HSP60. Epitope mapping studies suggest that this antibody binds to a linear sequence of 6 amino acids of Chlamydia HSP60 amino acids 117-122.

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.

Specifications

• Antigen: HSP60
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites with 0.05% sodium azide
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Clone: A57-E4
• Conjugate: Unconjugated
• Gene Alias: 60 kDa chaperonin; 60 kDa heat shock protein; 60 kDa heat shock protein, mitochondrial; 60kDa; Chaperonin 60; CPN60; GROEL; heat shock 60kD protein 1 (chaperonin); heat shock 60kDa protein 1; heat shock 60kDa protein 1 (chaperonin); Heat shock protein; heat shock protein 1 (chaperonin); heat shock protein 60; heat shock protein 60 (liver); heat shock protein 65; heat shock protein family D (Hsp60) member 1; heat shock protein, 60 kDa; HLD4; HSP; Hsp60; HSP-60; Hsp60s1; HSP65; HSP-65; Hspd1; Hspd1-30p; HuCHA60; hypothetical protein; I79_011398; mitochondrial matrix protein P1; P1 protein; P60 lymphocyte protein; RCJMB04_7g5; short heat shock protein 60 Hsp60s1; SPG13; Unknown (protein for IMAGE:7943409)
• Immunogen: Recombinant Chlamydia trachomatis HSP60.
• Regulatory Status: RUO
• Target Species: Bacteria
• Product Type: Antibody
• Isotype: IgG1

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov