HSP60 Monoclonal Antibody (LK2), APC, Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA545112

Catalog No. PIMA545112

Description

0.25 μg/mL of MA5-45112 was sufficient for detection of HSP60 in 10 μg of heat shocked HeLa cell lysate by colorimetric immunoblot analysis using goat anti-mouse IgG as the secondary antibody.∣Detects approximately 60kDa.

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.

Specifications

• Antigen: HSP60
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 2.15mM MES, potassium phosphate, sodium phosphate with 1.033mM EDTA and no preservative
• Gene Accession No.: P10809, P18687, P19882, P31081, P49818, P63038, P63039, Q5ZL72
• Gene Symbols: HSP60, HSPD1
• Immunogen: Recombinant human HSP60
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Bacteria, Bovine, Canine, Chicken, Fish, Guinea Pig, Hamster, Human, Insect, Mouse, Nematode, Non-human Primate, Plant, Pig, Rabbit, Rat, Yeast
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot
• Clone: LK2
• Conjugate: APC
• Gene: HSPD1
• Gene Alias: 60 kDa chaperonin; 60 kDa heat shock protein; 60 kDa heat shock protein, mitochondrial; 60kDa; Chaperonin 60; CPN60; GROEL; heat shock 60kD protein 1 (chaperonin); heat shock 60kDa protein 1; heat shock 60kDa protein 1 (chaperonin); Heat shock protein; heat shock protein 1 (chaperonin); heat shock protein 60; heat shock protein 60 (liver); heat shock protein 65; heat shock protein family D (Hsp60) member 1; heat shock protein, 60 kDa; HLD4; HSP; Hsp60; HSP-60; Hsp60s1; HSP65; HSP-65; Hspd1; Hspd1-30p; HuCHA60; hypothetical protein; I79_011398; mitochondrial matrix protein P1; P1 protein; P60 lymphocyte protein; RCJMB04_7g5; short heat shock protein 60 Hsp60s1; SPG13; Unknown (protein for IMAGE:7943409)
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100349912, 100689473, 100715481, 15510, 3329, 424059, 478854, 492279, 511913, 63868, 850963
• Content And Storage: 4° C
• Isotype: IgG1