Invitrogen™ HSP90 alpha Monoclonal Antibody (2G5.G3), APC

Catalog No.	Quantity
PIMA545180	200 μg

Catalog No. PIMA545180 Supplier Invitrogen™ Supplier No. MA545180

Description

Mouse Monoclonal Antibody

0.5 μg/mL of MA5-45180 was sufficient for detection of HSP90alpha in 20 μg of heat shocked HeLa cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 90kDa. HSP90 alpha -specific (>96% alpha -specific by ELISA).

Heat shock proteins (HSP) are proteins that are expressed in response to various biological stress, including heat. HSP90 is a 90 kDa protein that is induced under stress conditions, but is also one of the most abundant cellular proteins found under non-stress conditions. HSP90 has been found to be associated with a number of other intracellular proteins, including steroid receptors, actin, tubulin, and some kinases. It has been suggested that HSP90 is necessary to maintain structural integrity of at least some steroid receptors to allow for ligand binding during receptor activation.

Specifications

• Antigen: HSP90 alpha
• Applications: ELISA, Western Blot, Immunocytochemistry, Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: 2G5.G3
• Concentration: 1 mg/mL
• Conjugate: APC
• Formulation: 2.48mM MES, 95.46mM phosphate with 2mM EDTA and no preservative; pH 7.4
• Gene: Hsp90aa1
• Gene Accession No.: P07900, P07901, P82995
• Gene Alias: 86kDa; 89kDa; 90-kDa heat shock protein; 90-kDa heat shock protein alpha; akineto; AL024080; AL024147; EL52; epididymis luminal secretory protein 52; epididymis secretory sperm binding protein Li 65p; fb17b01; heat shock 86 kDa; heat shock 90kD protein 1, alpha; heat shock 90kD protein 1, alpha-like 4; heat shock 90kD protein, alpha-like 4; heat shock 90kDa protein 1, alpha; heat shock 90kDa protein 1, beta; Heat shock protein; heat shock protein 1, alpha; heat shock protein 86; heat shock protein 90; heat shock protein 90 alpha family class A member 1; heat shock protein 90, alpha (cytosolic), class A member 1; heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1; heat shock protein 90-alpha 1; heat shock protein 90kDa alpha (cytosolic), class A member 1; heat shock protein 90kDa alpha family class A member 1; heat shock protein alpha; Heat shock protein HSP 90-alpha; Heat shock protein HSP 90-alpha 1; heat shock protein HSP90 alpha; heat shock protein hsp90alpha; heat shock protein, 1; heat shock protein, 86 kDa 1; heat shock protein, 89 kDa; Heat shock protein90; HEL-S-65p; HSP; HSP 86; HSP 90 alpha; hsp4; HSP86; Hsp86-1; Hsp89; HSP89A; HSP90; hsp90a; hsp90a protein; hsp90a.1; hsp90aa1; hsp90aa1.1; hsp90alpha; HSP90N; HSPC1; Hspca; HSPCA protein; HSPCAL1; HSPCAL4; HSPN; hypothetical protein; LAP2; LAP-2; Lipopolysaccharide-associated protein 2; LPS-associated protein 2; renal carcinoma antigen NY-REN-38; slo; sloth; TSTA; Tumor-specific transplantation 86 kDa antigen; wu:fb17b01; zgc:86652
• Gene Symbols: Hsp90aa1
• Host Species: Mouse
• Immunogen: Recombinant Full Length Human HSP90alpha Protein.
• Purification Method: Protein G
• Quantity: 200 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 15519, 299331, 3320
• Target Species: Human, Mouse, Rat
• Content And Storage: 4°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov