Invitrogen™ HSP90 alpha Monoclonal Antibody (M10E3R), FITC

Catalog No.	Quantity
PIMA545088	100 μg

Catalog No. PIMA545088 Supplier Invitrogen™ Supplier No. MA545088

Description

Mouse Monoclonal Antibody

A 1:1,000 dilution of MA5-45088 was sufficient for detection of HSP90a in 10 μg of HeLa by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Detects 90 kDa. Does not detect HSP90 beta.

Heat shock proteins (HSP) are proteins that are expressed in response to various biological stress, including heat. HSP90 is a 90 kDa protein that is induced under stress conditions, but is also one of the most abundant cellular proteins found under non-stress conditions. HSP90 has been found to be associated with a number of other intracellular proteins, including steroid receptors, actin, tubulin, and some kinases. It has been suggested that HSP90 is necessary to maintain structural integrity of at least some steroid receptors to allow for ligand binding during receptor activation.

Specifications

• Antigen: HSP90 alpha
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: M10E3R
• Concentration: 1 mg/mL
• Conjugate: FITC
• Formulation: PBS, 9.1mM sodium bicarbonate with 581mM DMSO, 123mM ethanolamine and no preservative; pH 7.4
• Gene: Hsp90aa1
• Gene Accession No.: P07900
• Gene Alias: 86kDa; 89kDa; 90-kDa heat shock protein; 90-kDa heat shock protein alpha; akineto; AL024080; AL024147; EL52; epididymis luminal secretory protein 52; epididymis secretory sperm binding protein Li 65p; fb17b01; heat shock 86 kDa; heat shock 90kD protein 1, alpha; heat shock 90kD protein 1, alpha-like 4; heat shock 90kD protein, alpha-like 4; heat shock 90kDa protein 1, alpha; heat shock 90kDa protein 1, beta; Heat shock protein; heat shock protein 1, alpha; heat shock protein 86; heat shock protein 90; heat shock protein 90 alpha family class A member 1; heat shock protein 90, alpha (cytosolic), class A member 1; heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1; heat shock protein 90-alpha 1; heat shock protein 90kDa alpha (cytosolic), class A member 1; heat shock protein 90kDa alpha family class A member 1; heat shock protein alpha; Heat shock protein HSP 90-alpha; Heat shock protein HSP 90-alpha 1; heat shock protein HSP90 alpha; heat shock protein hsp90alpha; heat shock protein, 1; heat shock protein, 86 kDa 1; heat shock protein, 89 kDa; Heat shock protein90; HEL-S-65p; HSP; HSP 86; HSP 90 alpha; hsp4; HSP86; Hsp86-1; Hsp89; HSP89A; HSP90; hsp90a; hsp90a protein; hsp90a.1; hsp90aa1; hsp90aa1.1; hsp90alpha; HSP90N; HSPC1; Hspca; HSPCA protein; HSPCAL1; HSPCAL4; HSPN; hypothetical protein; LAP2; LAP-2; Lipopolysaccharide-associated protein 2; LPS-associated protein 2; renal carcinoma antigen NY-REN-38; slo; sloth; TSTA; Tumor-specific transplantation 86 kDa antigen; wu:fb17b01; zgc:86652
• Gene Symbols: Hsp90aa1
• Host Species: Mouse
• Immunogen: Purified HSP90.
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3320
• Target Species: Human
• Content And Storage: 4°C, store in dark
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a