Invitrogen™ HSP90 beta Monoclonal Antibody (MBH90B)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA110373

Catalog No. PIMA110373

Description

This antibody recognizes the EEVHHG epitope within the N-terminal part of Hsp90 beta an ubiquitously expressed intracellular protein with calculated Mw of 83.3 kDa, however, migrating as a 90 kDa band under reducing SDS-PAGE conditions.

Heat shock proteins (HSP) are expressed in response to various biological stresses, including heat. HSP90 is a 90 kDa protein that is induced under stress conditions, but is also one of the most abundant cellular proteins found under non-stress conditions. HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90 has been found to be associated with a number of other intracellular proteins, including steroid receptors, actin, tubulin, aryl hydrocarbon (Ah) receptor, and some kinases.

Specifications

• Antigen: HSP90 beta
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
• Gene Accession No.: P08238, P11499, Q76LV1
• Gene Symbols: Hsp90ab1
• Immunogen: Peptide corresponding to the EEVHHGEEEVEC sequence within N-terminal part of human Hsp90 (aa 3-14).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Bovine
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: MBH90B
• Conjugate: Unconjugated
• Gene: Hsp90ab1
• Gene Alias: 90kDa; 90-kDa heat shock protein beta; AL022974; C81438; D6S182; heat shock 84 kDa; heat shock 90 kDa protein; heat shock 90kD protein 1, beta; heat shock 90kDa protein 1, beta; heat shock cognate protein HSP 90-beta; Heat shock protein; heat shock protein 1, beta; heat shock protein 90 alpha (cytosolic), class B member 1; heat shock protein 90 alpha family class B member 1; heat shock protein 90 beta; heat shock protein 90 kDa; heat shock protein 90 kDa alpha class B member 1; heat shock protein 90kDa alpha (cytosolic), class B member 1; heat shock protein 90kDa alpha family class B member 1; Heat shock protein HSP 90-beta; heat shock protein, 84 kDa 1; HSP; HSP 84; HSP 90; Hsp84; Hsp84-1; Hsp90; hsp90 beta; HSP90AB1; HSP90B; HSP90-beta; HSPC2; HSPCB; retinal degeneration slow protein; RP1-302G2.1; TSTA; Tumor-specific transplantation 84 kDa antigen; Unknown (protein for IMAGE:7943063)
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 15516, 3326, 767874
• Content And Storage: 4°C, do not freeze
• Form: Liquid