Invitrogen™ HSP90 beta Polyclonal Antibody, Alexa Fluor™ 647

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA3012A647

Catalog No. PIPA3012AY

Description

PA3012A647 detects heat shock protein 90 beta (HSP90) from human, monkey, mouse, and rat tissues and cells. This antibody does not detect HSP86. The PA3012A647 immunogen is a synthetic peptide corresponding to residues P(2) E E V H H G E E E V E(13) of mouse HSP84. The N-terminal regions of HSP84 and HSP86 show the largest difference in amino acid sequence.

Heat shock proteins (HSP) are expressed in response to various biological stresses, including heat. HSP90 is a 90 kDa protein that is induced under stress conditions, but is also one of the most abundant cellular proteins found under non-stress conditions. HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90 has been found to be associated with a number of other intracellular proteins, including steroid receptors, actin, tubulin, aryl hydrocarbon (Ah) receptor, and some kinases.

Specifications

• Antigen: HSP90 beta
• Classification: Polyclonal
• Conjugate: Alexa Fluor 647
• Gene: Hsp90ab1
• Gene Alias: 90kDa; 90-kDa heat shock protein beta; AL022974; C81438; D6S182; heat shock 84 kDa; heat shock 90 kDa protein; heat shock 90kD protein 1, beta; heat shock 90kDa protein 1, beta; heat shock cognate protein HSP 90-beta; Heat shock protein; heat shock protein 1, beta; heat shock protein 90 alpha (cytosolic), class B member 1; heat shock protein 90 alpha family class B member 1; heat shock protein 90 beta; heat shock protein 90 kDa; heat shock protein 90 kDa alpha class B member 1; heat shock protein 90kDa alpha (cytosolic), class B member 1; heat shock protein 90kDa alpha family class B member 1; Heat shock protein HSP 90-beta; heat shock protein, 84 kDa 1; HSP; HSP 84; HSP 90; Hsp84; Hsp84-1; Hsp90; hsp90 beta; HSP90AB1; HSP90B; HSP90-beta; HSPC2; HSPCB; retinal degeneration slow protein; RP1-302G2.1; TSTA; Tumor-specific transplantation 84 kDa antigen; Unknown (protein for IMAGE:7943063)
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15516, 301252, 3326
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P08238, P11499, P34058
• Gene Symbols: Hsp90ab1
• Immunogen: Synthetic peptide corresponding to residues P(2) E E V H H G E E E V E(13) of mouse HSP84.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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