Invitrogen™ HSP90 Monoclonal Antibody (D7A), APC

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA545157

Catalog No. PIMA545157

Description

2 μg/mL was sufficient for detection of HSP90 alpha in 20 μg of heat shocked HeLa cell lysate as well as in 100 ng of human HSP90 alpha protein by colorimetric immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary. Recognizes 90kDa.approximately Can isolate complexes of HSP90, Src kinase and cec37.

HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 and mitochondria (Chen et al., 2005 ).

Specifications

• Antigen: HSP90
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.2
• Gene Accession No.: O02705, P07900, P07901, P08238, P11499, P11501, P30946, P30947, P34058, P82995, Q04619, Q76LV1, Q76LV2
• Gene Symbols: HSP90AA1, HSP90AB1
• Immunogen: Full length protein HSP90 purified from chicken brain.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Rabbit, Bovine, Pig, Chicken
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot, Microarray
• Clone: D7A
• Conjugate: APC
• Gene: HSP90AB1
• Gene Alias: 86kDa; 89kDa; 90kDa; 90-kDa heat shock protein; 90-kDa heat shock protein alpha; 90-kDa heat shock protein beta; AL022974; AL024080; AL024147; C81438; D6S182; EL52; epididymis luminal secretory protein 52; epididymis secretory sperm binding protein Li 65p; heat shock 84 kDa; Heat shock 86 kDa; heat shock 90 kDa protein; heat shock 90kD protein 1, alpha; heat shock 90kD protein 1, alpha-like 4; heat shock 90kD protein 1, beta; heat shock 90kD protein, alpha-like 4; heat shock 90kDa protein 1, alpha; heat shock 90kDa protein 1, beta; Heat shock protein; heat shock protein 1, alpha; heat shock protein 1, beta; heat shock protein 86; heat shock protein 90 alpha (cytosolic), class B member 1; heat shock protein 90 alpha family class A member 1; heat shock protein 90 alpha family class B member 1; heat shock protein 90 beta; heat shock protein 90 kDa; heat shock protein 90, alpha (cytosolic), class A member 1; heat shock protein 90kDa alpha (cytosolic), class A member 1; heat shock protein 90kDa alpha (cytosolic), class B member 1; heat shock protein 90kDa alpha family class A member 1; heat shock protein 90kDa alpha family class B member 1; heat shock protein HSP 90-alpha; Heat shock protein HSP 90-beta; heat shock protein, 1; heat shock protein, 84 kDa 1; heat shock protein, 86 kDa 1; heat shock protein, 89 kDa; HEL-S-65p; HSP; HSP 84; HSP 86; HSP 90; hsp4; HSP84; Hsp84-1; HSP86; Hsp86-1; Hsp89; HSP89A; Hsp90; HSP90A; Hsp90aa1; Hsp90ab1; HSP90B; HSP90-BETA; HSP90N; HSPC1; HSPC2; HSPCA; HSPCA protein; HSPCAL1; HSPCAL4; HSPCB; HSPN; LAP2; LAP-2; lipopolysaccharide-associated protein 2; LPS-associated protein 2; renal carcinoma antigen NY-REN-38; retinal degeneration slow protein; TSTA; Tumor-specific transplantation 84 kDa antigen; tumor-specific transplantation 86 kDa antigen; Unknown (protein for IMAGE:7943063)
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100338694, 100358690, 15516, 15519, 281832, 299331, 301252, 3320, 3326, 396188, 396742, 397028, 423463, 767874
• Content And Storage: 4°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov