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Invitrogen™ HSPA14 Polyclonal Antibody
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Catalog No. PIPA596580
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100 μL
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PIPA596580 100 μL
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Catalog No. PIPA596580 Supplier Invitrogen™ Supplier No. PA596580
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ASEFQRSFKH DVRGNARAMM KLTNSAEVAK HSLSTLGSAN CFLDSLYEGQ DFDCNVSRAR FELLCSPLFN KCIEAIRGLL DQNGFTADDI NKVVLCGGSS RIPKLQQLIK DLFPAVELLN SIPPDEVIPI GAAIEAGILI GKENLLVEDS LMIECSARDI LVKGVDESGA SRFTVLFPSG TPLPARRQHT LQAPGSISSV CLELYESDGK NSAKEETKFA QVVLQDLDKK ENGLRDILAV LTMKRDGSLH VTCTDQETGK CEAISIEIAS; Positive Samples: MCF7, SW620, COS-1, HeLa, Jurkat, Mouse spleen, Mouse brain, Mouse thymus; Cellular Location: Cytoplasm, cytosol.

The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent poly-peptide chains across cellular membranes and the regulation of protein folding. HSPA14 (heat shock 70kDa protein 14), also known as HSP70-4 or HSP70L1, is a 509 amino acid novel HSP protein derived from human dendritic cells. Belonging to the heat shock protein 70 family, HSPA14 is thought to promote dendritic cell maturation. It is also suggested that HSPA14 stimulates secretion of the proinflammatory cytokines interleukin 12p70 (IL-12p70), IL-1 beta, TNF alpha, and the chemokines IP-10, MIP-1 alpha, MIP-1 beta and normal T cell expressed and secreted (RANTES).
TRUSTED_SUSTAINABILITY

Specifications

Antigen HSPA14
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.26 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene HSPA14
Gene Accession No. Q0VDF9, Q99M31
Gene Alias 70kDa; heat shock 70 kDa protein 14; heat shock 70kDa protein 14; heat shock 70kDa protein 14 isoform 1 variant 3; Heat shock protein; heat shock protein 14; heat shock protein 4; heat shock protein family A (Hsp70) member 14; heat shock protein HSP60; heat shock protein hsp70-related protein; heat shock protein, 70 kDa 4; HSP; HSP60; Hsp70-4; HSP70L1; HSP70-like protein 1; HSP7E; HSPA14; hsr.1; NST-1
Gene Symbols HSPA14
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 240-509 of human HSPA14 (NP_0573832).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50497, 51182
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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