Invitrogen™ HSPA14 Recombinant Rabbit Monoclonal Antibody (SD08-48)

Catalog No.	Quantity
PIMA532413	100 μL

Catalog No. PIMA532413 Supplier Invitrogen™ Supplier No. MA532413

Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent poly-peptide chains across cellular membranes and the regulation of protein folding. HSPA14 (heat shock 70kDa protein 14), also known as HSP70-4 or HSP70L1, is a 509 amino acid novel HSP protein derived from human dendritic cells. Belonging to the heat shock protein 70 family, HSPA14 is thought to promote dendritic cell maturation. It is also suggested that HSPA14 stimulates secretion of the proinflammatory cytokines interleukin 12p70 (IL-12p70), IL-1 beta, TNF alpha, and the chemokines IP-10, MIP-1 alpha, MIP-1 beta and normal T cell expressed and secreted (RANTES).

Specifications

• Antigen: HSPA14
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
• Classification: Recombinant Monoclonal
• Clone: SD08-48
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
• Gene: HSPA14
• Gene Accession No.: Q0VDF9, Q6AYB4, Q99M31
• Gene Alias: 70kDa; heat shock 70 kDa protein 14; heat shock 70kDa protein 14; heat shock 70kDa protein 14 isoform 1 variant 3; Heat shock protein; heat shock protein 14; heat shock protein 4; heat shock protein family A (Hsp70) member 14; heat shock protein HSP60; heat shock protein hsp70-related protein; heat shock protein, 70 kDa 4; HSP; HSP60; Hsp70-4; HSP70L1; HSP70-like protein 1; HSP7E; HSPA14; hsr.1; NST-1
• Gene Symbols: HSPA14
• Host Species: Rabbit
• Immunogen: Synthetic peptide within Human HSPA14 aa 51-100.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 307133, 50497, 51182
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG