HSPA14 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA572469

Catalog No. PIPA572469

Description

The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent poly-peptide chains across cellular membranes and the regulation of protein folding. HSPA14 (heat shock 70kDa protein 14), also known as HSP70-4 or HSP70L1, is a 509 amino acid novel HSP protein derived from human dendritic cells. Belonging to the heat shock protein 70 family, HSPA14 is thought to promote dendritic cell maturation. It is also suggested that HSPA14 stimulates secretion of the proinflammatory cytokines interleukin 12p70 (IL-12p70), IL-1 beta, TNF alpha, and the chemokines IP-10, MIP-1 alpha, MIP-1 beta and normal T cell expressed and secreted (RANTES).

Specifications

• Antigen: HSPA14
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HSPA14
• Gene Alias: Heat shock 70 kDa protein 14; HSP70-like protein 1Heat shock protein HSP60; HSPA14; HSP60; HSP70L1; HSP7E
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 50497, 51182
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.77 mg/mL
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: Q0VDF9, Q99M31
• Gene Symbols: HSPA14
• Immunogen: KLH conjugated synthetic peptide between 80-109 amino acids from the N-terminal region of human Hsp 60
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG