HSPA5 Mouse anti-Human, Biotin, Clone:1H11-1H7, Abnova™

Catalog No.	Quantity
89-334-123	100 μg

Catalog No. 89-334-123 Supplier Abnova Corporation Supplier No. MAB17320

Description

Mouse monoclonal antibody raised against human HSPA5.

When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as ′immunoglobulin heavy chain-binding protein′ (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM]

Specifications

• Antigen: HSPA5
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: 1H11-1H7
• Conjugate: Biotin
• Description: heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
• Dilution: Immunocytochemistry (1:100)
  Immunofluorescence (1:100)
  Western Blot (1:2000)
  The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide)
• Gene: HSPA5
• Gene Alias: BIP, FLJ26106, GRP78, MIF2
• Host Species: Mouse
• Immunogen: His-tagged human HSPA5.
• Quantity: 100 μg
• Gene ID (Entrez): 3309
• Target Species: Human
• Content And Storage: Store at -20°C.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b