Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Invitrogen™ HSPB11 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5116808
Description
Positive Samples: A-549, 293T, Mouse kidney, Mouse brain, Rat thymus Immunogen sequence: MRKIDLCLSS EGSEVILATS SDEKHPPENI IDGNPETFWT TTGMFPQEFI ICFHKHVRIE RLVIQSYFVQ TLKIEKSTSK EPVDFEQWIE KDLVHTEGQL QNEEIVAHDG SATYLRFIIV SAFDHFASVH SVSAEGTVVS NLSS.
HSPB11 (Heat shock protein beta-11), also known as IFT25, was originally identified as a small heat shock protein. Recently it has been identified as a component of IFT complex B. It has been demonstrated that IFT25 is not required for ciliary assembly but is required for proper Hedgehog signaling, which in mammals occurs within cilia. Cilia lacking IFT25 have defects in the signal-dependent transport of multiple Hedgehog components and fail to activate the pathway upon stimulation.
Specifications
HSPB11 | |
Polyclonal | |
Unconjugated | |
Hspb11 | |
2900042B11Rik; C1orf41; Heat shock protein; Heat shock protein beta-11; heat shock protein family B (small) member 11; heat shock protein family B (small), member 11; HSP; Hspb11; Hspb11 heat shock protein family B (small), member 11; HSPC034; HSPCO34; IFT25; intraflagellar transport 25 homolog; intraflagellar transport protein 25 homolog; Placental protein 25; placental protein 25 homolog; PP25 | |
Rabbit | |
Affinity chromatography | |
RUO | |
51668, 685284, 72938 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
0.90 mg/mL | |
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
Q9D6H2, Q9Y547 | |
Hspb11 | |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human HSPB11 (NP_0572102). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction