HSPB8 Monoclonal Antibody (OTI1E3), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA501210

Catalog No. 50-167-2354

Description

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Specifications

• Antigen: HSPB8
• Classification: Monoclonal
• Concentration: 0.88 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9EPX0, Q9UJY1
• Gene Symbols: HSPB8
• Immunogen: Full length human recombit protein of human HSPB8 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI1E3
• Conjugate: Unconjugated
• Gene: HSPB8
• Gene Alias: CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 113906, 26353
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid