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HSPB8 Monoclonal Antibody (OTI1E3), TrueMAB™, OriGene
SDP

Catalog No. 501672354
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30 μL
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50-167-2354 100 μL
50-254-2457 30 μL
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Catalog No. 50-167-2354 Supplier OriGene Supplier No. TA501210
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Mouse Monoclonal Antibody

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Specifications

Antigen HSPB8
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
Classification Monoclonal
Clone OTI1E3
Concentration 0.88 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene HSPB8
Gene Accession No. Q9EPX0, Q9UJY1
Gene Alias CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
Gene Symbols HSPB8
Host Species Mouse
Immunogen Full length human recombit protein of human HSPB8 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 113906, 26353
Target Species Human, Rat
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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