HSPB8 Mouse anti-Human, Mouse, Rat, Clone: 3C12-H11, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527706
DescriptionThe protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
|PBS with 50% glycerol and 0.09% sodium azide; pH 7.4|
|Q9EPX0, Q9JK92, Q9UJY1|
|Alpha crystallin C chain, CMT2L, CRYAC, DHMN2, H11, Heat shock 22kDa protein 8, HMN2, HSB8, HSPB8, HSP22|
|113906, 26353, 80888|
|ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|His-tagged human recombit HSP22|
|Human, Mouse, Rat|
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