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HSPB8 Mouse anti-Human, Mouse, Rat, Clone: 3C12-H11, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527706

Catalog No. PIMA527706


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Description

Description

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Specifications

Specifications

HSPB8
Monoclonal
1 mg/ml
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Q9EPX0, Q9JK92, Q9UJY1
Alpha crystallin C chain, CMT2L, CRYAC, DHMN2, H11, Heat shock 22kDa protein 8, HMN2, HSB8, HSPB8, HSP22
Mouse
IgG1, kappa
100 μg
-20°C
Primary
113906, 26353, 80888
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
3C12-H11
Unconjugated
HSPB8
Liquid
Hspb8
His-tagged human recombit HSP22
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Documents
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