HSPB8 Mouse anti-Human, Rat, Clone: OTI1E3, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF501210

Catalog No. 50-166-0240

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Specifications

• Antigen: HSPB8
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: HSPB8
• Gene Alias: CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 113906, 26353
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI1E3
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q9EPX0, Q9UJY1
• Gene Symbols: HSPB8
• Immunogen: Full length human recombit protein of human HSPB8 produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG2a