HSPB8 Mouse anti-Human, Rat, Clone: OTI1E3, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-0240	100 μg

Catalog No. 50-166-0240 Supplier OriGene Supplier No. CF501210

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Specifications

• Antigen: HSPB8
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: OTI1E3
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: HSPB8
• Gene Accession No.: Q9EPX0, Q9UJY1
• Gene Alias: CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
• Gene Symbols: HSPB8
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human HSPB8 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 113906, 26353
• Target Species: Human, Rat
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2a