Invitrogen™ HSPB8 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518103

Catalog No. PIPA518103

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Specifications

• Antigen: HSPB8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HSPB8
• Gene Alias: Alpha-crystallin C chain; AU018630; AW413033; CMT2L; Cryac; crystallin, alpha C; D5Ucla4; DHMN 2; DHMN2; E2IG1; E2-induced gene 1 protein; H11; H11K; heat shock 22kDa protein 8; heat shock 27kDa protein 8; Heat shock protein; heat shock protein 8; heat shock protein B8; heat shock protein beta-8; heat shock protein family B (small) member 8; HMN 2; HMN2; HMN2A; HSB8; HSP; HSP20-like; Hsp22; HSPB 8; Hspb8; OTTHUMP00000239768; PP1629; Protein kinase H11; small stress protein-like protein HSP22
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 26353
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9UJY1
• Gene Symbols: HSPB8
• Immunogen: Synthetic peptide sequence (NELPQDSQEVTCT) corresponding to the C-terminus amino acids of HSPB8 (aa 184-196).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov