Invitrogen™ HSPBP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA564461

Catalog No. PIPA564461

Description

Immunogen sequence: KLKVKSAFLL QNLLVGHPEH KGTLCSMGMV QQLVALVRTE HSPFHEHVLG ALCSLVTDFP QGVRECREPE LGLEELLRHR CQLLQQHEEY QEELEFCEKL LQT Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 100%.

HspBP1 is an Hsp70-interacting protein that was first isolated from a human heart cDNA library using the yeast two-hybrid system. The ATPase domain of Hsp70 binds HspBP1 and upon binding, inhibits Hsp70 chaperone activity. More recently HspBP1 was found to promote nucleotide dissociation from Hsc70 (3) and is capable of altering the confirmation of the Hsp70 ATPase domain. HspBP1 is capable of regulating any Hsp70 activity that requires ATPase.

Specifications

• Antigen: HSPBP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HSPBP1
• Gene Alias: 1500019G21Rik; FES1; Heat shock protein; heat shock protein-binding protein 1; HSP; hsp70 interacting protein; hsp70-binding protein 1; Hsp70-binding protein 2; hsp70-interacting protein; hsp70-interacting protein 1; Hsp70-interacting protein 2; HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1; HSPA (Hsp70) binding protein 1; HSPA binding protein, cytoplasmic cochaperone 1; Hspbp; HSPBP1; HspBP2; LOW QUALITY PROTEIN: hsp70-binding protein 1; MGC128574 protein; PP1845; SPA ) binding protein, cytoplasmic cochaperone 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23640
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NZL4
• Gene Symbols: HSPBP1
• Immunogen: Recombinant protein corresponding to Human HSPBP1. Recombinant protein control fragment (Product #RP-103930).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG