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Description
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq]
Specifications
Specifications
| Antigen | HSPD1 |
| Applications | Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | LK-2 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against human HSPD1. |
| Dilution | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Immunoprecipitation (10 ug/mL) Western Blot (0.25 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.2 (50% glycerol, 0.1mM PMSF). |
| Gene Alias | CPN60/GROEL/HLD4/HSP60/HSP65/HuCHA60/SPG13 |
| Gene Symbols | HSPD1 |
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