Invitrogen™ HSPE1 Polyclonal Antibody

Catalog No.	Quantity
PIPA577824	100 μg

Catalog No. PIPA577824 Supplier Invitrogen™ Supplier No. PA577824

Description

Rabbit Polyclonal Antibody

Immunohistochemistry samples may be prepared using Bouin's Fixative solution. 1 μg/mL of PA5-77824 was sufficient for detection of Cpn10 in 10 μg of Hela lysates by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody. Detects approximately 10kDa.

The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. Heat shock proteins (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the low molecular weight HSPs, the immunophilins and the HSP 110 family. The low molecular weight family includes HSP 10, HSP 20, HSP 27 (Heme Oxygenase 1), HSP 32 and HSP 40. Chaperonins are ubiquitous, indispensable proteins that facilitate protein folding in an ATP-dependent manner, enhancing the yield of properly folded substrate protein under conditions where spontaneous folding does not occur. Chaperonins are typified by the E. coli heat-shock proteins GroEL and GroES (HSP 10). HSP 10 is a heptameric ring of identical 10 kDa subunits that binds to each end of GroEL to form a symmetric, functional heterodimer.

Specifications

• Antigen: HSPE1
• Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.02% sodium azide; pH 7.3
• Gene: HSPE1
• Gene Accession No.: P26772, P61603, P61604, Q64433
• Gene Alias: 10 kDa chaperonin; 10 kDa heat shock protein, mitochondrial; 10 kDa heat shock protein, mitochondrial; MOB-like protein phocein; 10kDa; 10kDa Chaperonin; CH10; chaperonin 10; Cpn 10; CPN10; cpn10 protein; early pregnancy factor; early-pregnancy factor; EPF; GROES; Heat shock 10 kD protein 1 (chaperonin 10); heat shock 10 kDa protein 1 (chaperonin 10); heat shock 10 protein 1; heat shock 105kDa/110kDa protein 1; heat shock 10kD protein; heat shock 10kD protein 1 (chaperonin 10); heat shock 10kDa protein 1; heat shock 10kDa protein 1 (chaperonin 10); heat shock protein; heat shock protein 1 (chaperonin 10); heat shock protein 105; heat shock protein 105 kDa; heat shock protein 105 kDa; LOW QUALITY PROTEIN: heat shock protein 105 kDa; heat shock protein family E (Hsp10) member 1; heat shock protein family E (Hsp10) member 1 L homeolog; heat shock protein family H (Hsp110) member 1; HSP; hsp10; hsp105; hsp105a; hsp105b; hsp110; Hspe1; hspe1.L; Hsph1; hsph1-a; hsph1-b; mitochondrial 10 kDa heat shock protein; mitochondrial chaperonin 10; MOB family member 4, phocein; MOB1, Mps One Binder kinase activator-like 3; MOB4; MOBKL3; mob-like protein phocein; mt-cpn10; PREI3; preimplantation protein 3; XELAEV_18045050mg; zgc:86747
• Gene Symbols: HSPE1, hspe1.L, LOC100357698
• Host Species: Rabbit
• Immunogen: Human Cpn10 peptide AA 91-101.
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100350401, 100357698, 106024963, 15528, 25462, 281833, 3336, 394775, 397575, 414669, 478855
• Target Species: Human, Mouse, Rat, Canine, Rabbit, Bovine, Pig, Guinea Pig, Frog
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov