HSPG2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 196751AP150UL

Catalog No. 50-173-2479

Description

The antibody is specific to HSPG2.

Perlecan is a major heparan-sulfate proteoglycan (HSPG) found within all basement membranes and cell surfaces. Because of its strategic location and ability to store and protect growth factors, perlecan has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a coreceptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.

Specifications

• Antigen: HSPG2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HSPG2
• Gene Alias: heparan sulfate proteoglycan 2, HSPG, HSPG2, Perlecan, PLC, PRCAN, SJA, SJS, SJS1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15530, 313641, 3339
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.27 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P98160
• Gene Symbols: Hspg2
• Immunogen: Peptide
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG